PolySaccharides PolyPeptides

Natures Healing Miracles

By Doctor Howard Peiper
​​

  
Chapter 1: Origin and Function


           Rice is the culinary culture as well the basis for economical solvency in many societies.  For example, the Burmese cultural history embraces ancient folklore where the Kachins people of northern Myanmar were sent forth from the center of the Earth with seeds of rice.  These people were directed to a wondrous country where everything was perfect and where rice grew well.  Today rice remains as their leading crop and a most revered food.  In Bali, it is believed that the Lord Vishnu caused the Earth to give birth to rice, and the God Indra taught the people how to raise it.  In both myths rice is considered a gift of the gods.  Even in modern times the people of both countries treat rice with according reverence and its cultivation is tied to elaborate rituals.

           By contrast, a Thai myth tells of rice being a gift of animals rather than of gods.  This was a time when Thailand had been engulfed by severe weather and wracked with floods.  After the land finally drained, people came down from the hills where they had taken refuge only to discover that all the plants had been destroyed and there was little to eat.  They survived through hunting although animals were scarce.  According to the writings, one day the people saw a dog coming across a field and handing on the dog's tail were bunches of long, yellow seeds.  They planted these seeds.  Rice grew, and hunger disappeared.  Throughout Thailand today, tradition builds that "the precious things are not pearls and jade but are the five grains," of which rice is the first.  While most modern Thai's may intellectually dismiss its supernatural role, they cannot deny the enormous cultural importance of rice in their country, and also in most of the other rice-producing and rice-consuming countries of the world

Science Meets Myth
     
            Scientists have utilized ancient Thai folk medicine, techniques, and theory combined with modern and sophisticated technology to produce a unique polysaccharides/polypeptide functional food.  It is called Alphaglycanology TM, and it is a proprietary and proprietary and innovative process employing biotechnology and nanotechnology.  The purpose of the Alphaglycanology technique is to mechanically hydrolyze polysaccharides 1 and polypeptides 2 in cereal grains, from specially selected fractions of rice grains, harvested at the proper age.  This grain is grown in an area where the soils are alkaline in nature and continuously enriched with natural organic matter containing abundant spirolina3 found in the water.  The rice is organically grown, free of pesticides and insecticides and is not modified in any way.

By bonding the polysaccharides/polypeptides together under controlled humidity, temperature and pressure, a naturally hydrolyzed alpha-glycan is formed.  Thus, producing an incredibly beneficial functional food that when consumed is recognized by the cells of the body as a biological fuel for utilization by the mitochondria for the production for the cellular energy or ATP (adenosine triphosphate).  A recent study demonstrated a significant increase of ATP in mitochondria metabolism if 54 percent.
     
The special characteristics of this proprietary functional food, processed with the Alphaglycanology process, allows for the 100 percent bioavailability.4  When consumed, these unique functional genomic nutrients are readily assimilated facilitating an improvement of the intracellular environment.  This is essential for DNA repair and the resulting enhanced gene expression.  Correspondingly, the environment manifested in the body is vitally essential for optimal health.  The Alphaglycanology process employed by scientists to produce the polysaccharides/polypeptides has shown its ability to effectively preserve the functional value of the phytonutrients5. 

            Scientists have found that when certain species of grains are grown under optimal conditions, and are harvested at the proper age, they contain top quality functional and essential nutrients such as specific polysaccharides, polypeptides, the amino acids, vitamins, minerals, and antioxidants (gamma oryzanol, tocopherol tocoprienols).  Rice grains meetings these criterial are perfectly suited to enhance the cellular energy (ATP) production of the mitochondria for DNA repair and cellular regeneration.    .They can combat free radicals and enhance the detoxification process establishing an anabolic (building) phase so that the body’s natural healing power can function optimally.  The unique combination of these antioxidants, organic mineral amino acid compounds, and polysaccharides has the ability to stimulate the body to naturally regulate a state of homeostasis (when the body is in balance).  This results in balanced levels of blood sugar, cholesterol, triglycerides, blood pressure, body temperature, electrolytes, and pH.

            There are several different sources of polysaccharides/polypeptides: aloe vera, medicinal mushrooms (reishi, mitake, (shiitake), and nutritional primary yeast.  Below is the difference between a beta-glucan polysaccharides/polypeptides and an alpha-glycan processed polysaccharides/polypeptides.

Alpha-Glucan (Glycan) vs Beta-Glucan

            Alpha-Glucan (Glycan) linkages can be easily broken down by alpha-amylase.  Therefore, single units of glucose and amino acid can be utilized by cells and white blood cells.  Glucose will be used to produce energy (ATP).  With energy and the correct type of amino acid, white blood cells will have all the necessary raw materials to produce a certain type of antibody wherever foreign material enters our body.  While there is no foreign material, cells can use energy and the correct type of amino acid for the improving normal repairing process.

            Beta Glucan is highly soluble, but the beta linkage is difficult to be broken down due to the limited amount of glucoamylase.  Beta-glucan acts as a foreign material.  It touches the receptor and stimulates white blood cells to generate a certain type of antibody, a process that requires energy and the correct type of amino acid from out body.   If the body does not have enough energy and/or the correct type of amino acid, the production process for a certain type of antibody is not effective.  If the production of a certain type of antibody is too effective and generates excessive antibody while there is no real foreign material, some undesirable symptoms might arise.

pH Balance

            The scale used to measure the body’s acidity and alkalinity is called pH, normally measured in a range from one to fourteen .  A neutral solution, neither acidic nor alkaline, has a pH of seven; acid is less than seven, alkaline is more than seven.  The blood must be kept within the very narrow range of pH 7.4 to maintain homeostasis (balance).

            Unfortunately, the average North American diet is very high in acid foods, such as sugar, refined carbohydrates and starch.   These are not conducive to maintaining proper pH balance in the body and raise acid levels.  To prevent disease from getting a foothold in this acid environment it is imperative that homeostasis be restored, which can be accomplished by adding trace minerals to the diet.  This acidic condition is caused by metabolic waste.  When trace minerals are in sufficient quantity they bind with the waste and flush it out through the urine thus returning the body to a more balanced state.

            Excessive acid waste literally attacks the joints, tissues, muscles, organs, and glands, causing minor to major dysfunction.  If it affects the joints, arthritis may develop; effects on the muscles may result in myofibrosis (aching muscles); attacks on the organs and glands, can cause a myriad of illnesses.  The more acidic the body is, the more compromised the immune system becomes.  A constant diet of foods excessively high in protein and sugar results in a more acidic body and weakens the immune system allowing conditions like chronic fatigue syndrome, cancer, MS, and arthritis to gain a foothold.

            pH-balancing the body slightly more on the alkaline side than on the acid should be a daily goal.  Because polysaccharides/polypeptides are made from a whole food that is grown in an alkalized, mineral-enriched environment, it has the ability to facilitate a slightly alkaline pH balance.  When the pH is balanced in the body, it is able to totally absorb all the nutrients from foods and supplements.  Polysaccharides/polypeptides efficiently creates and maintains a pH-balanced body.

Detoxification

            An important function of polysaccharides/polypeptides is its ability to detoxify6 the body.  Avoi9ding contact with toxins on a daily basis is virtually impossible, and a buildup of these toxins within the body results in many forms of illnesses.  Cleanliness, externally and internally, is essential to good health.  Polysaccharides/polypeptides assist this process because it works on the entire body to remove toxins from the system.  When these toxins are eliminated, polysaccharides/polypeptides help support and strengthen the glandular system helping the body heal itself.

            The colon and the bowel become the depository for all waste material after food nutrients are extracted into the bloodstream.  Decaying food ferments and forms gases as well as second and even third generations toxins.  Thus the colon becomes a breeding ground for putrefactive bacteria, viruses, parasites, yeast and more.  Because of polysaccharides/polypeptide’s fiber-like structure the peristalsis movement of the colon is strengthened and bowel movements are healthier and more regular, better facilitating the elimination process.  Healthy intestines are the body’s second immune system.  Therefore, it is essential to keep them free of putrefied waste.

Chapter Two: The Immune System

            The immune system’s basic function is to protect us against infection, illness and disease of all kinds.  It fights off thousands of predatory environmental and infectious microoganisms, which can invade and damage virtually every part of the body.  The immune system has the ability to expel pathogens (virus’ bacteria, etc.)  toxic chemicals, and tumorous cells that are generated through mutation.  It also aids the body in tissue repair and healing and strives to maintain homeostasis (balance) in the body.

            The immune system involves a finely tunes, highly integrated series of events that destroy a would-be invader.  Once the immune system identifies an unwanted guest, it brings an awesome array of chemical and cellular weapons to banish the perpetrators.  This non-specific, intricate, and elaborate immune response can readily discriminate between the “self” and “non-self”, that is, cells that are a normal part of the body versus alien organisms.  The innate intelligence of the immune system insures that the body does not turn on itself and lose the ability to distinguish between the “good and bad” cells. 

Autoimmunity

            When the immune system loses the ability to distinguish between self and non-self it may develop an auto-immunity (the body manufacturing antibodies and T-cells directed against its own cells, cell components or even specific organs).  Autoimmune responses include allergies, asthma, rheumatoid arthritis, dermatitis, systemic lupus erythematosus, multiple scleroses, fibromyalgia and also may be the underlying factorin numerous chronic conditions.  When the body is under constant exposure to various pathogens the immune system will become over stimulated resulting in autoimmunity.

Weakened Immunity

            When the immune system is working properly we remain healthy.  However, the immune system can and does become compromised.  This may be a result of the following: incessant environmental assault such as from: exposure to pseudo-estrogens; pesticides and pollutants in air, food and water; certain medications; persistent metabolic damage, (for example, high free-radical stress); poor nutrition, chronic infection or advancing age; and strenuous physical activity and emotional stress.  As you can see, numerous diverse factors may compromise the immune system and disturb its exquisitely balanced components.

            It is no secret that our body is put under physical and emotional stress warding off the above-mentioned, multi-faceted assaults.  When our bodies become overwhelmed the regulatory features of the immune system weaken and become less effective resulting in: fatigue; loss of stamina and energy; frequent colds and infections; loss of appetite and weight loss; fever and night sweats; skin rashes and cold sores; diarrhea; increased severity of allergy symptoms; swollen lymph nodes; and other symptoms of immune deficiencies. 

            In time these conditions can exacerbate the initial symptoms into more serious immune-compromised conditions (such as chronic fatigue, cancer, HIV, etc).  It is widely believed that cancer may be caused by a decline in the immune system function attributed to aging, lifestyle and other factors.  The AIDS virus is known to destroy our immune cells and trigger a multitude of bodily system breakdowns.

            Over time, normal cell-mediated immunity may become inadequate or malfunction.  This may allow multiple genetic mutations in the same location (malignant transformations) resulting in abnormal growth.  The degenerative process is generally quite slow and elusive.  It may take many years and many bouts of illness to truly manifest itself where a diagnosis is levied.

            Polysaccharides/polypeptides have strong immune stimulating properties.  Health care practitioners have consistently observed the therapeutic benefits produced by polysaccharides/peptides for a wide range of health problems.  It has been shown to promote vast improvement in causes of many common but serious problems, ranging from cancer, chronic fatigue syndrome, high blood pressure, rheumatoid arthritis, Parkinson’s Alzheimer’s, diabetes, hepatitis, high cholesterol, tumors, Tourette’s, irritable bowel syndrome.7

                To maintain good health, minimize the frequency and severity of all illnesses, and recover quickly, it is imperative that the immune system function efficiently and optimally.  The more hazards we expose the body to, the greater the call for the immune system to maintain our health.  Natural immune support is very important, making dietary additions such as polysaccharides/polypeptides a primary consideration.

Chapter Three: Polysaccharides/Polypeptides and Anti-Aging

            Aging- it’s happening to everybody.  Time is accelerating the aging process faster than we’d like.  But, even though the hourglass tells us we’re older the passage of time isn’t really what ages us.  The ageing culprit is the process that creates a reduction of healthy cells in our body

            Cells don’t age; they’re sloughed off as their efficiency diminishes and are replaced by new ones.  With proper nutrition, cell restoration continues in excess of what is generally considered a normal life expectancy.  Industrialized civilization breeds environmental pollutants, diets full of chemicals and additives, vitamin and mineral deficiencies, and the overuse of prescription drugs.  This menu of assaults gives rise to an early retirement in the cemetery.  Today, industrialized countries boast statistics that claim 80 percent of the population in excess of 65 years old is chronically ill, usually with arthritis, diabetes or high blood pressure. 8

                The key to long life is emotional and physical balance (homeostasis).  Our general loss of vitality and disease originates from poor diet, lifestyle choices, or from long term environmental assaults.  Yet, there is hope.  Youthfulness is restored from the inside, by strengthening our lean body mass, metabolism, and immune response with good nutrition, regular exercise, fresh air, and a positive mental attitude.

Fountain of Youth

            Through my research I have determined that polysaccharides/polypeptides can play a big role in our search for the “fountain of youth.”  The antioxidant properties of polysaccharides/polypeptides prevent body components from destruction by free radicals – a key to anti-aging.

            The three important contributors to aging are: cell and tissue damage caused by free radicals,9 reduced immune response, and enzyme depletion in the body due to diets composed of enzyme deficient foods (cooked or processed.)

            Free radicals, (highly active compounds produced when molecules react with oxygen,) play a key role in the deterioration of the body.   Under assault from chemical-ized foods and environmental pollutants, our bodies generate excesses of these cell damagers.  After years of free-radical assaults cells become irreplaceably lost from major organs such as the lungs, liver, kidneys, the brain, and particularly our nervous system.  This loss is seen as a primary cause of aging.

            Alzheimer’s, Parkinson’s, and Multiple Sclerosis are thought to be associated with the aging process due to three potent neurotoxins, Beta-Amyloid, Glutamate, and Peroxides, that can lend to nerve cell damage and destruction.  These molecules disrupt and destroy normal nerve cell function.

            Studies reveal that polysaccharides/polypeptides have been shown to preserve nerve cell function by supplying food and nutrients at the cellular level.  The concept is simple.  Provide the cell with food easily recognized and utilized the cell’s DNA (the “molecule of life”) to generate energy.  This will provide the vehicle for repairing cell damage.

This is incredible news for people with Alzheimer’s and Creutzfeldt-Jakob diseases.  Both illnesses manifest when a neurotoxin, called Beta Amyloid, deposits itself in the brain and disrupts communication between nerve cells.  Scientists have tried to treat the diseases by attacking the protein deposits but to date this approach has not been successful.

            A new study shows that by helping nerve cells produce normal proteins these connections can actually be rejuvenated.10   In this study, nerve cells exposed to three of the most potent neurotoxins were ultimately protected from damage after adding polysaccharides/polypeptides to the medium.  A degree of cellular regeneration of the nerve dendrites and axons was also seen.  These extraordinary results have consistently been observed in subsequent research.

            Superoxide dismutase (SOD) is an extremely potent antioxidant enzyme that fights cellular damage from single oxygen molecules (also known as free radicals).  As an enzyme, SOD has particular value helping to protect against cell destruction. .  Research suggests that SOD may be the most important enzyme in the body for the control of free radicals, keeping our cell membranes young, supple, and healthy (anti-aging).  Although SOD has been sold as a supplement, research shows that oral SOD is destroyed by the digestive system before it can fight free radicals and repair damaged joints.  This suggests that the most viable means of building healthy levels of SOD in the body would be to consume natural food substances that bind protein to SOD and therefore deliver it via the digestive system to the body, without being destroyed in the gut.  Polysaccharides/polypeptides facilitate that process and increase the level of SOD in the body.

            There are numerous antiixidants11 made by the body as well as antioxidants found through supplementation or in our diets.  Nutrients like vitamins E and C, beta-carotene and the trace mineral selenium root out and free radicals that make it past the antioxidants enzymes.  It is necessary to support the body’s own production of antioxidant enzymes (SOD) because they remove free radicals three to ten times faster than the nutrient its own antioxidant enzymes, and that is what polysaccharides/polypeptides facilitates. 

            Polysaccharides/polypeptides are premier agents for reversing the causes of aging by utilizing the following:
            1.  Increasing the level of SOD (superoxide dismutase), the master antioxidant;
            2.  Enhancing nucleotide production for DNA repair;
            3.  Enhancing cellular environment for improved genetic expression;
            4.  Increasing pro-enzyme and probiotic (friendly intestinal bacteria) activities.

            “Since I started taking a polysaccharides/polypeptides functional food my sexual performance has been enhanced.  I am 61 years old, in a relationship with a 44 year old female and was dismayed when I found my sexual energy diminishing.  I thought of taking Viagra, however, my naturopathic doctor suggested trying the polysaccharides/polypeptides.  It worked and I am grateful that I listened to him,”
Julio Cabral, Mexico City, Mexico

            “I took a polysaccharides/polypeptides product for general maintenance and to my grateful surprise, I discovered that at least 50 percent of my face wrinkles have disappeared, and my skin tightened up.  I have tried everything short of a surgical face lift.  I am happy to discover an alternative that works.  This will be a youth saver for all post-menopausal women (and men)!
Nina A., East Canaan, CT


  
Chapter 4:  The Brain and Mental Function

            The brain is a delicate and complex structure.  As the control center of all physical and intellectual activity in the body it utilizes as many as 100 billion different cells, with millions and millions of neurons forming a seemingly innumerable number of connections.  It is responsible for all of our internal functions and our interactions with our external surroundings.  In order to maintain this relationship, the brain must be functioning properly.  For us to enjoy life to the fullest, we need to be in control.   Optimal functioning is desired for optimal interaction.  Around the age of 30, neurons (brain cells) begin to die (or go dormant).  After this age, they die at a faster rate then they are replaced, thus beginning the degenerative process that becomes more and more obvious as we get older.

            Neurons are large cells, which require large amounts of energy and proper nutrition to function normally.  The brain receives 12-20 percent of the body’s total blood supply and uses 15-20 percent of the body’s total inhaled oxygen which, along glucose, is used by the brain to produce and use 15-20 percent of the body’s total ATP 9adenosine triphosphate) energy.  Unlike most other cells, which can burn fat or glucose for their energy needs, neurons can only burn glucose.  Under normal conditions our brain cells typically consume 50 percent of the total blood glucose.  Therefore, neurons and cells in the brain are dependent upon a continuous and uninterrupted rich blood supply to maintain normal energy metabolism and avoid cellular injury or death.

            Under normal conditions, with adequate oxygen supply, these neurons convert glucose into (ATP) for three reasons:
Cell maintenance, since neurons don’t reproduce and must last a lifetime, they are continually expanding energy to repair or replace cell parts – cell membranes segments, microtubules, mitochondria, etc.
Neurotransmitter operation: neurons use ATP to produce, transport, package, secrete, and re-uptake neurotransmitters such as acetylcholine and serotonin which provide vital cell-to-cell communication
Electrical energy: huge amounts of ATP are necessary to facilitate the frequent discharges of electrical energy from the neuron through the cell body to the transmitting end – the axon.  For this electrical process to occur there must be a rapid and continuous exchange of sodium and potassium ions back and forth across the neuronal membranes.

              Over a lifetime, there can be low and subtle memory loss resulting from brain-energy losses due to cerebral arteriosclerosis, ministrokes, neurotoxins (glutamate, beta-amyloid, and peroxides), or brief interruptions of brain oxygen supply (often caused by blood vessel spasm).  In addition to memory impairment, this brain energy crisis may also cause occasional confusion or lapses in concentration, and learning difficulties.

             For reasons we are only beginning to understand, the neuron replacement process is far more evident in some people than in others.  One octogenarian will be fully self sufficient remembering not only what they need to do for that day, but also the details of some event that happened over 40 years ago.  However, others may not remember their own telephone numbers or the names of their children or grandchildren.

            At a more advanced stage the brain energy crisis may show itself as senility or senile dementia, and eventually may terminate in coma or death.  The severity of dementia is directly correlated to the loss of functional brain tissue independent of the primary neuropathology.  If someone’s brain is not working correctly it is largely because of brain disease (such as Alzheimer’s Parkinson’s, brain tumor, infection, vascular disturbances), injury (such as from brain trauma, stroke, stress neurotoxins, alcohol or drugs), or deficiencies of EFA’s (essential fatty acids) or B complex vitamins.

Symptoms of Cognitive Deterioration

            Cognitive deterioration can involve the loss or decline of any of the cognitive functions including:
  • Memory
  • Orientation
  • Information fixation
  • Attention
  • Perception
  • Judgment

Major contributing factors to cognitive degeneration may include the following:
  • Chronic circulatory problems in the brain: This includes a variety of medical conditions that decrease the delivery of blood flow to the brain reducing glucose, oxygen, and nutrients to the brain cells;
  • Various cerebral disorders: These include Alzheimer’s or Parkinson’s diseases;
  • Cerebral hemorrhage;
  • Transient ischaemic attacks (TIA), an interrupted blood flow to the brain;
  • Various brain toxic substances:  We cite examples such as alcohol, opiates, (morphine, heroin), cocaine, amphetamines, hallucinogens, (STP, LSD, marijuana, etc.) and neurotoxins (glutamate, beta amyloid and peroxides);
  • Various prescribed medications: These may be very toxic to the brain and may cause memory loss, confusion or depression, and may have an adverse effect on brain function.  Various prescription medications can include: pain killers, antidepressants, tranquilizers, sleeping pills, antihistamines, corticosteroids, heart and blood pressure medication.

        Individuals with vascular disease or dementia attributed to Alzheimer’s often have a disturbance in antioxidant balance that may predispose one to increased oxidative stress.  This would then be a potential therapeutic area for antioxidant supplementation.

Enhanced memory function
            Polysaccharides/polypeptides are recommended for cerebral circulatory disorders such as memory problems, acute stroke aphasia (loss of power of expression), apraxia (inability to coordinate movements), motor disorders, dizziness and other cerebro-vestibular (inner ear) problems, and headache.  Polysaccharides/polypeptides can often be beneficial for acute or chronic ophthalmologic diseases of various origins, and may improve vision.  Polysaccharides/polypeptides also have a very powerful stimulating effect on memory because of its effect on the brain’s metabolism.

            Polysaccharides/polypeptides increase the metabolism in the brain several ways:
  • It increases the rate at which brain cells produce ATP (which is the cell molecule that creates energy);
  • It speeds up the use of glucose in the brain;
  • It speeds up the use of oxygen in the brain.

          The result is that the cells of the brain can better retain information causing the individual to remember more Polysaccharides/polypeptides have been reported as showing promising benefits for the following conditions:
  • Stroke
  • Vertigo
  • Meniere’s Syndrome
  • Sleep disorders
  • Mood changes
  • Tourette’s syndrome
  • ADD/ADHD
  • Depression
  • Tinnitus
  • Migraine
  • Tinnitus
  • Migraine headaches
  • Macular degeneration
  • Convulsions
  • Multiple Sclerosis
  • Cerebral Palsy

Polysaccharides/polypeptides Increase neurotransmitters

            Polysaccharides/polypeptides stimulate cognitive enhancement primarily through its influence important neurotransmitters.  These neurotransmitters relay information between neurons and rely on specialized brain chemicals to function properly.  While memory is an extremely complex phenomenon transmission is even more complex.  There are more than one hundred different neurotransmitters that have been identified.

            Depressed levels of certain neurotransmitters are associated with psychiatric disorders.  Depression has been linked with depressed levels of serotonin and Parkinson’s has been linked with depressed levels of dopamine.  An overabundance of dopamine is associated with Tourette’s syndrome (an involuntary movement and vocal disorder, often socially disabling).

            Neurotransmitters are responsible for the transmission of information between neurons, indicating that they are necessary for all cognitive function.

            Polysaccharides/polypeptides support neuronal transmission by:
Increasing levels of noradrenaline (thinking, learning planning);
  • Balancing levels of dopamine (libido, information processing);
  • Increasing levels of acetylcholine (memory);
  • Increasing levels of serotonin (mood, sleep, balances appetite, lowers substance cravings).

       Please take note that depression is a symptom of insufficient serotonin levels, which is often caused by prolonged exposure to stressors.  Scientists have found that a positive therapeutic effect of polysaccharides/polypeptides was shown in patients who exhibited pronounced depressive states of varied origins.  In a recent study, a substantial decrease or complete disappearance of the clinical manifestation of depression was noted in 65 percent of the patients.  Serotonin has the ability to help the body adapt to stress.  Polysaccharides/polypeptides can raise serotonin levels, thereby helping the body resist chronic stress and mood disorders related to low levels of serotonin.

      “I cannot say enough good things about this miraculous food.  For nine years I had suffered from Multiple Sclerosis, experiencing vision problems, muscle weakness, fatigue, dizziness, and burning sensations in my feet.  After taking a polysaccharides/polypeptides functional food three times a day for several months, all of my symptoms disappeared I am able to walk without a limp and climb stairs without the aid of a railing.  I feel like I have truly found a miracle in my life.”
Paula Barnes, Washington State

  
Chapter Five: Polysaccharides/Polypeptides and Diabetes

            America is in the midst of a growing epidemic that now affects more than 18 million people.  The medical pharmaceutical industry calls this metabolic disorder “diabetes” which occurs when the body is unable to properly utilize insulin to help regulate glucose or blood sugar levels in the body.    If blood sugar concentrations rise a number of critical body functions are affected such as metabolism, fluid body produces too much insulin and loses its ability to respond appropriately a condition develops known as insulin resistance syndrome.  It is estimated that nearly 80 million Americans have this problem, and most of them don’t even know it.

            Polysaccharides/polypeptides works at the cellular and molecular level providing each and every cell with the energy it needs to metabolize glucose, rid the body of toxins and waste products, and begin cellular regeneration.  The molecular structure of polysaccharides/polypeptides allow for improved absorption and assimilation of glucose through direct absorption into the cell.  The properties in polysaccharides/polypeptides help keep the glucose-energy metabolism system finely tuned.  This dramatically decreases the workload of the liver by enhancing direct cellular absorption of glucose, reducing the amount of insulin release and therefore decreasing the risk of other metabolic disorders.

            Polysaccharides/polypeptides will improve health conditions linked with diabetes.  For example, one may experience:

  • Better balance of blood glucose
  • Reduced fatigue and more energy
  • Enhanced natural production of antioxidants to reduce free radical damage
  • Less damage to glucose/energy metabolism;
  • Better healing of diabetic gangrene, greatly reducing the risk of amputation

          “L.H. age 69, is amazed that he can walk from his bed to the bathroom without excruciating pain.  Since being diagnosed Type II Diabetes in 1993, L.H. has suffered burning and painful tingling sensations in his toes and feet.  He experienced such pain that he couldn’t bear to walk even the short distance to the bathroom without something on his feet.  Like most of us L.H. was very skeptical of the restorative properties of the polysaccharides/polypeptides.  The pain in his feet and the daily annoyance of taking up to five pills to control his blood sugar prompted him to give polysaccharides/polypeptides a try.  Is he ever glad that he did!  After just three weeks of taking only one scoop a day in the morning, L.H. has cut out his medications by 75 percent.  Not only has his blood sugar stabilized, he now has enough energy to go to the gym.  Perhaps best of all, he walks with much less pain than before taking a polysaccharides/polypeptides product.”
Tien Huynh, New Orleans LA

           “I’ve had serious health problems during the last ten years, including Type II Diabetes and colds that would develop into walking pneumonia.  Allergic reactions to antibodies made it all the most difficult to control the illnesses.  At the beginning of 2003 I was told about a new whole food polysaccharides/polypeptides product which I began taking in a cup of green tea.

      “I have had circulation problems for years and although the condition has improved, my feet were still numb and cold to the touch.  My remedy for this was to apply
Vicks Vapor Rub on my feet and wear socks to keep them warm.  It helped, but didn’t sole the problem.  I was quite surprised at what happened on the second day of using polysaccharides/polypeptides when I realized that I had forgotten to use the Vicks.  My feet starting itching and I couldn’t stop moving my toes and rubbing my feet together.  It was evident that the circulation was returning to my feet and they were healing!  I was excited because I feared my circulation problems might lead to serious complications, common in diabetes.

      “After reporting my newfound ‘cure’ to my doctor in Las Colinas, he said that he would monitor my progress and reduce my medication if needed.  I checked my blood pressure and blood glucose twice a day and noticed that my blood pressure had dropped the first day I took a polysaccharides/polypeptides product.  The average for the last two weeks was 122/68 (had previously tested at 131/88) and my blood glucose average for two weeks was III and had been 128.  When I was first diagnosed with Type II Diabetes there were times when my eyesight would blur and I was unable to focus.  After taking the product, I find I rarely use glasses now for reading or writing.

      “I had been on the polysaccharides/polypeptides product for six weeks and noticed many changes.  I was now free of rashes from allergies.  The brown spots on my arms and hands were fading, my eyebrows were growing thicker and there was a marked improvement in my digestion.  My metabolism must have increased because I lost inches.  My breakthrough came during the second week after I began taking the product.  I often use a full-body vibrator with heat and never felt the vibration in my ankles and feet until now.  I now also find that my energy is unbelievable strong.”
Donna Marshall, Grand Prairie, TX


  
Chapter Seven:  Polysaccharides/Polypeptides and Cancer

      Cancer high risk groups are generally linked to a genetics and age, although stress is currently being considered a contributor because it weakens the immune system and makes the body less likely to control cancer cell growth.  Cancer is the abnormal growth of cells in the body.  It is a result of normal cell mutation through its genetic chromosome material, RNA and DNA.  Normally cells replicate themselves continually at a rate synchronous with normal growth and repair in a manner specific for its purpose in the body.  Cancerous cells multiply faster than normal and lose normal differentiation sometimes forgetting to die.

      Chemical and environmental factors may be responsible for 90 percent of all cancers.  Elevated risk of cancer from hormone imbalances and toxic buildup in the cells, especially in the colon, can actually be linked to environmental assaults from pesticides and meat hormone residues.  While cancer is one of the leading causes of death today, many types of cancer are preventable.

      To keep cancer from compromising the body we must strengthen the immune system by naturally enhancing the cellular rejuvenation process.  Polysaccharides/polypeptides can be a facilitator of this process.  Polysaccharides/polypeptides can be a facilitator of this process.  As the body’s cells become healthier, they will stimulate the immune system and improve its functionality.  Also, because polysaccharides/polypeptides balance the pH in the body, the oxygen level is raised.  Since cancer cannot live in a highly oxygenated environment its survival will be compromised.

      Some aggressive forms of cancer treatment often are exceedingly stressful to the body.  Side effects can be debilitating, for example, hair loss and the “wasting disease” associated with chemotherapy.  Patients using polysaccharides/polypeptides have shown a reduction in the severity of these side effects.  Used in conjunction with conventional therapy, polysaccharides/polypeptides can strengthen the immune function and provide a more therapeutic platform for recovery.

      “I am 49 years old and have had rheumatoid arthritis.  I have been in the UCLA experimental program on and off for many years, taking a prescription drug to control the pain.  I am afflicted with receding gums and I visit my dentist every three months to have him check on my condition.

      “One day when I was taking a shower I noticed there was a small lump on my neck.  The fear of cancer immediately crossed my mind.  The next day I saw my doctor and he told me to have an ultrasound and x-ray on my throat.  I was right it was cancer.

      “My uncle had been using a polysaccharides/polypeptides functional food and suggested it to me.  Most of the people know that I am skeptical about new products but, at this point, I had nothing to lose.  During my check-up one month later, my doctor was surprised that the lump had completely disappeared and advised that I continue taking the product since it seemed to be helping my condition.  By the way, my gums are less painful and I am not as tired as I used to be. Polysaccharides/polypeptides have helped me at just the right time.”
Linda Arnold, Los Angeles, CA

      “I’ve been taking a polysaccharides/polypeptides product for a month on the advice of my naturopathic doctor.  Prior to taking this product, I had just quite chemotherapy treatments and my body was greatly debilitated from its side effects.  I started a new regimen, which included polysaccharides/polypeptides and noticed that my mood, energy and my feeling of well-being has returned.  Today I am feeling as good as I felt before contracting cancer.  I’m confident that this regime will help me to continue being strong and cancer free.”
Barbara Bankey, Albuquerque, NM

  
  
Chapter Eight:  Polysaccharides/Polypeptides and Chronic Fatigue 

      Most researchers believe that Chronic Fatigue Syndrome (CFS) is a result of mixed infections with several pathogens such as environmental pollutants and chemical contaminants.   These contribute to CFS by reducing our immune response, thereby allowing the syndrome to develop.  In addition, growing evidence points to the fact that exhausted adrenal glands from high stress life-styles and a imbalance in the hypothalamic-pituitary-adrenal axis can exacerbate the illness.  CFS is a response (or lack of immune response) to the ever increasing mental, emotional and physical stressors in our environment.  As our body’s immunity drops lower and lower almost any disruption in our health or emotional state can be the final trigger for Chronic Fatigue Syndrome.

      Research indicates polysaccharides/polypeptides can help balance immune system functions in two ways and, therefore, guard against CFS.  Polysaccharides/polypeptides can directly and specifically stimulate the immune system by increasing the body’s resistance to toxins that may accumulate during the development of infection when the immune system is first called into action.  Polysaccharides/polypeptides help to stabilize the hormone cortisol, which is responsible for how we respond to stress.   Stress suppresses immunity and destroys our resistance to various forms of bacterial or viral attacks.   When we are under stress, a greater portion of the body’s energy is expensed.  Chronic exposure to stress results in a lowered immune response and decreased health.

      “Due to chronic fatigue traced to anemia, in 1999 I retired from being a very active office manager.  I consulted with several medical doctors who were unable to correct the situation.  As time passed I became more fatigued and my blood pressure began to rise during exercise or stress.  I was under constant medical attention without receiving any appreciable results.  I was also diagnosed as being oxygen deprived (to the brain).  In July, 2002, I became immobile and had to be placed on oxygen 100 percent of the time.  If I removed the oxygen my skin became blue within minutes.  In addition, my appetite disappeared and my stomach began to expand, similar to conditions seen in a starved child in Africa.  I was for all practical purposes trapped in my living room by day and night.  I did not see any hope.

      “In December, 2002, I was introduced to a polysaccharides/polypeptides product.  I took the recommended three scoops a day.  On the third day I was able to go off the oxygen for a very short period of time and make breakfast for my husband for the first time in six months.  On the fourth day I was able to go to the shopping mall and have my hair done (two hours without oxygen).  On the firth day I actually cleaned my house. 
During Christmas of 2002 my family celebrated what I considered to be a miracle.

      “On the first day of January, 2003 only a month after I started taking polysaccharides/polypeptides, I was relying on the oxygen only 5 percent of the time.  My appetite was back to normal, my energy returned, and I felt like my old self.  I believe that this product will extend my life for many years.”
Toni Garcia, Albuquerque, NM


  
Chapter Ten:  Polysaccharides/Polypeptides and Arthritis

      Normally considered to be an inevitable part of aging some schools of thought deem the condition of arthritis to be a result of toxic body trying to rid itself of waste.  When salt combines with other wastes it precipitates out of the blood and lymph fluids, forming abrasive deposits.  Ending up in the joints, these deposits may cause a condition known as bursitis and arthritis.  Minerals normally carry these deposits out of the body.  Our Western diets are deficient in the minerals needed by the body.  This is due to over farming of the soil without  mineral replacement.  Foods grown in this manner (including both supermarket and organic varieties), are lacking the essential minerals needed by the body to function as designed.

      Arthritis is one of the long-term effects of mineral imbalance and free radical damage.  Mineral imbalances manifest as an acid condition in the body develops because our PH is not in homeostasis.  With specific dietary changes, supplementation with a polysaccharides/polypeptides functional food and a good mineral supplement, the pH can be better balanced resulting in arresting the pain and degeneration of even advanced arthritic conditions.

      Because polysaccharides/polypeptides are processed from specific rice grains that are grown in highly alkalized and mineralized soil, taking polysaccharides/polypeptides daily will keep the pH of our body balanced.  Cleansing and supporting the immune system will also help reduce the effects of arthritis.

      "Be patient and polysaccharides/polypeptides will astound you and being you joy and happiness.  I have learned that if it takes five years to get sick, it could take possibly five months to get well.  Polysaccharides/polypeptides have made such a great difference in my overall health that I advise everyone to take polysaccharides/polypeptides,”  With these words Jeff Thompson explains that it saved him from a long history of health problems, most significantly, severe arthritis sinus and hay fever.  Relief did not come overnight to Jeff.  Indeed, everyone who takes a polysaccharides/polypeptides functional food benefits at a different rate- some within hours or days, others weeks or months.  Jeff fell into the latter category.

      “My wife, Shamasi and I started taking a polysaccharides/polypeptides product in the middle of January, 2003.  For years she had suffered from arthritis pain in both hands.  By the end February her pain was gone.  We both are experiencing wonderful results from taking this functional food.  I’ve had problems with ulcers and they are gone and what has really surprised me is that my Rosacea (red face) has almost disappeared.  I am a true believer in this fantastic product.”
Jim and Shamsi McMahan, Sugar Land, TX


Chapter Eleven: Research and Studies

Polysaccharides/polypeptides may prevent neuron vulnerability in human neuroblastoma cells

(preliminary, unpublished data)
A study by Dean, M. Ishak, PhD MD,
College of Complementary Medicine, Malaysia

Abstract (Preliminary data)
      Objective: The current study investigated the neurotrophic and neuroprotective action of an unique formulation of Polysaccharides/polypeptides, which consists of carbohydrate, crude protein, and essential minerals by using pressure and mechanical hydrolysis to make a complex formulation.
      Methods: Using neuronal cell lines prepared from the LA-n-5 (Los Angeles Neuroblastoma) for Alzheimer’s disease (AD) in complete media and treated with indicated manner, inverted microscopic evaluated morphological and biochemical analysis were conducted to determine the neutrophic and neuroprotective properties of polysaccharides/polypeptides.
      Results: Results of this analysis demonstrated that polysaccharides/polypeptides significantly decreased neuronal cell death, a cellular marker of memory formation.  Dose response analysis (experiment going on) indicated that the lowest effective concentration of polysaccharides/polypeptides exerted the minimal neutrophic effect.  Results of neuroprotection studies demonstrated that polysaccharides/polypeptides induced highly significant neuroprotection against beta-amyloid, peroxides, and glutamate induced toxicity.
      Discussion:     Abnormality of glucose/energy metabolism shows relation to AD (1,2,3,4).  Polysaccharides/polypeptides may prevent impairment of glucose/energy metabolism and may improve the ability to neurons to reduce the levels of free radicals (scavengers) and thereby affect ATP levels.  (11,12).
      Conclusion:
Polysaccharides/polypeptides induced cellular markers of memory function in neurons critical to memory and vulnerable to negative effects of aging, cellular degeneration and Alzheimer’s disease.  Results of the current study could demonstrate the cellular mechanism of a polysaccharides/polypeptides on cognitive function and possible intervention in Alzheimer’s disease.
      Key Words:  Polysaccharides/polypeptides, Cell Death, Alzheimer’s disease (AD), Neuroprotective.

Introduction
Alzheimer’s disease:  A scientific mystery and major impact.  Abnormality of glucose/energy metabolism shows relation to Alzheimer’s disease (1,2,3,4).  Degenerative and cell death are major causes in AD.
Polysaccharides/polypeptides are a complex formulation that consists of carbohydrate, crude protein and essential minerals by using pressure and mechanical hydrolysis to make a complex formulation (5)
Polysaccharides/polypeptides are very safe because they contain phytochemicals that have components of carbohydrates, crude protein and essential minerals by using pressure and mechanical hydrolysis to make a complex formulation.  Evidence by observation from animal (pig) data showed that polysaccharides/polypeptides could decrease morbidity from Ataxia (polysaccharides/polypeptides may improve cerebral blood flow).  In clinical use we found that polysaccharides/polypeptides improve short and long term memory (6)
LA-N-5 (Neuroblastoma cell lines) have been used for model of Alzheimer’s disease in vitro (7,8,9,10).

Objectives
To determine if polysaccharides/polypeptides may promote neutrophic and neuroprotective actions that show decreased cell death (Apoptosis) in the Alzheimer model in vitro.
To determine if polysaccharides/polypeptides show neutrophic and neuroprotective action in AD model and to determine what is the mechanism of polysaccharides/polypeptides.

For proposed mechanism of polysaccharides/polypeptides induced neuroprotection in AD model in vitro.

Materials and Methods
(1)  Neuronal culture
Neuronal cells lines were prepared from the LA-N-5; Los Angeles Neuroblastoma derived from bone marrow metastasis of four-month-old male patient.  Cells were propagated in RPMI 1640 supplemented with 10 percent FCS, 2mM glutamine, 50 IU/ml penicillin, 50 ug/ml streptomycin, and 1 ug/ml fungizone (complete medium).
(2)  Morphological analysis
By using inverted microscopic evaluated morphological analysis of LAN5 in indicated conditions.
(3)  Neuronal viability was determined by inclusion criteria of trypanblue.
(4)  The neutrophic and neuroprotective action of polysaccharides/polypeptides was determined by inducing other neurotoxic substrates ad indicated conditions.
       1.1  Estrogen deprivation exposure:  Neuronal viability was determined by estrogen deprivation exposure.
       1.2 Hydrogen peroxide exposure:  1uM H202 for 5 minutes at 37 deg. C. During exposure E2 or polysaccharides/polypeptides was added concurrently with H2O2.  After 5 min, the culture was rinsed two times with HBS, and Fresh medium with E2 or polysaccharides/polypeptides was replaced.
       1.3 Glutamate exposure: 0.2 uM Glutamate 20 min. at room temperature.
       1.4 Beta amyloid 25-35: 8 ug/ml AB25-36 24, at 37 deg. C.

Results
  • Neuroprotection by against other neurotoxic results:
  • Estrogen deprivation induced neurotoxicity
  • Hydrogen peroxide induced neurotoxicity
  • Glutamate induced neurotoxicity
  • Beta amyloid25-35 induced neurotoxicity
  • Dose dependent of polysaccharides/polypeptides shows neuroprotection against other neurotoxins

Discussion
Abnormality of glucose/energy metabolism shows relation to AD (1,2,3,4).  Polysaccharides/polypeptides may prevent impairment of glucose/energy metabolism and may improve the ability of neurons to reduce the levels of (“scavenger”) free radicals and thereby affecting ATP levels (11,12).

Conclusions
  • Polysaccharides/polypeptides, a functional food, contain a unique formation consisting of a complex form of carbohydrate, crude protein and essential minerals by using high pressure and mechanical hydrolysis to make a complete formulation designated polysaccharides/polypeptides.  Polysaccharides/polypeptides, in vitro, have consistently demonstrated that it prevents cell death from other neurotoxicity agents.
  • Polysaccharides/polypeptides induced cellular markers of memory function in neurons critical to memory and vulnerable to negative effects of aging, cellular degeneration and Alzheimer’s disease.  Results of the current study could demonstrate the cellular mechanism of polysaccharides/polypeptides on cognitive function and a possible intervention in Alzheimer’s disease.
  • In clinical application, polysaccharides/polypeptides, a functional food, may promote cellular mechanism in memory and neuronal survival and may be used as a nutritional survival and may be used as a nutritional supplement in aging, cellular degenerative processes and a possible use for preventing Alzheimer’s disease.

References
1. Blass, JP, Gibson, GE Shimada, M, Kihara, T, Watanabe, M, and Kurinioto,K, (1980) “Brain carbohydrate metabolism and dementia,”   Biochemistry of Dementia (Burman, D. and Pennock, C.A.,), Wiley, London, pp 121-134.
2. Blass, JP, Sheu, KFR, and Cederbaum, JM, (1988), “Energy metabolism in disorders of the nervous system,” Rev. Neurol, (Paris), 543-563.
3. Beal, MF, (1992), “Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative diseases?”  Ann. Neurol., 31, 110-123
4. Blass, JP, Sheu, KFR, and Tanzi, R, (1996), “a Ketoglutarate dehydrogenase in Alzheimer’s disease in Energy Metabolism,”  Neurodegenerative Diseases (Fiskum, G, ed), Plunum NY pp. 185-192. 
5. Laboratory report from Pacific Lab Services, Report No: /396-3971/LS/2001, Feb. 19th, 2001
Interview with Medical Doctors Testimonial No. 007, 018m 058 and 068
6. Preuss, U, Mandelhow, EM, (1988) “Mitotic phosphorylation of tau protein in neuronal cell lines resembles phosphorylation in Alzheimer’s disease, Eur J Cell Biol, 76 (2): 176-84.
7. Mesco, ER, Timiras, PS., “Tau ubiquitin protein conjugates a human cell line,”  Mech Ageing Dev  199; 61 (1): 1-9.
8. Davis, PK, Johnson, GV, (1994) “Monoclonal antibody Alz-50 reacts with bovine and human ser albumin,” J Neurosci Res,; 39(5): 589-94.
9. Fabrizi, C, Businaro, R, Lauro, GM, Starace, G, Fumagalli, L, (1999) “Activated alpha2 mascroglobulin increase beta amyloid (25-35)  induced toxicity in LA-N-5 human neuroblastoma cells,” Esp Neuro, l, 155(2): 252-9
10. Beal, MF, (1995), “Aging, energy, and oxidative stress in neurodegenerative diseases,”
Ann, Neurol, 38, 357-366
 11. Mattson, MP, (1994), “Mechanism of neuronal degeneration and preventive approaches: Quickening the pace of AD research,” Neurobiol, Ageing 15, (Suppl.2) S121-S125.


Report on Possible Solutions in the global Health Problems
(April 2002)
Dr. Mohamed Ahmed, M.D., President of the Association of Complementary Medicine, Malaysia

      The present food consumed by people in developed countries is predominantly processed food treated with pesticides, insecticides and siil nutrients of chemical nature.  The introduction of many different chemicals into the body along with the food we consume has interfered with normal functioning of cells both at their intrinsic and extrinsic functions.  It is now known that many proteins fold up into abnormal forms, called Rogue Proteins.  These abnormal forms can be the cause of a multitude of diseases.
      Example:  The underlying reason why Alzheimer’s and Creutzfeldt-Jakob diseases cause dementia is because small clusters of Beta Amyloid molecules – the misfolded protein – disrupt the junctions between nerve cells in rat brains.  (Prof. Denis Selkoe of Harvard Medical School and colleagues.)  While scientists are trying to produce Synthetic Peptides (called Synthetic Mini-Cheperonin) to destabilize the abnormal folding of the protein misfolding in the first place.
      Researchers believe that they have found the secret to correct this misfolding of proteins and sugar at the cellular level.  Research in vitro tests on neuronal cells shows that polysaccharides/polypeptides are able to protect the neurons from toxic materials like Beta Amyloid, Peroxides and Glutamate.
      Hypothesis is that polysaccharides/polypeptides are able to provide the glucose and amino acids necessary for normal protein and sugar folding, thus enabling cellular repair.
      Clinical studies in the form of evidence based studies prove the hypothesis.  Numerous testimonials and “clinical study results” have encouraged the scientists and clinicians to indulge further into research.
      With the support from the Ministry of Science and Technology for the research projects, scientists will move even faster.  More research, both in vitro and in vivo, is ongoing to further prove and to publish move findings.  This natural food, in its simplest form, has the solution for most of the modern ailments.  Instead of wasting millions of dollars on high tech surgery and medicines, we should turn to natural food, for solutions to the global problems.

Diabetic Study with Polysaccharides/polypeptides Bangkok, Thailand Oct. 2003
Dr. Mohamed Ishak M.D. Dr. B. Chalermporn M..D., Dr. Mark D. Smith N.D.
Introduction:  Type 2, adult onset, non-insulin dependent diabetes, affects about 85 percent of diabetics, striking one in 18.  With its complications, it is the third leading causes of death in the U.S.  It’s a chronic degenerative disease in which disturbances in normal insulin mechanisms impair the body’s ability to use carbohydrates.  Type 2 diabetics produce insulin, the hormone that helps convert food in to energy, but isn’t used properly (insulin resistance), causing glucose to build up in the bloodstream, depriving cells of the nutrients they need.
Test subjects:  702 individuals that were diagnosed with Type 2 Diabetes, by a physician.  The volunteers were given polysaccharides/polypeptides, a functional food, to take three times a day for 90 days.  They were tested at: 0 days, 30 days, 60 days and 90 days.
Final Results:  570 out of 702 people completed all four laboratory tests:  before taking this functional food 30 days, 60 days and 90 days after taking this product.  84.22 percent had improvement within 30 days 89.65 percent had improvement within 60 days 90.18 percent had improvement within 90 days.

Preliminary Efficacy Study of Polysaccharides/polypeptides in Multiple Sclerosis (Feb. 14 2003)15
Mark Dargan Smith N.D., PhD., Dean, University of National Medicine, New Mexico

Introduction
Multiple sclerosis (MS) affects 350,000 Americans.  With the exception of trauma, it is the most frequent cause of neurological disability beginning in the early to middle adulthood age groups.  MS is twice as common in females as in males and its occurrence is unusual before adolescence.  A person has an increased risk of developing the disease from the teen years to age forty with the risk gradually declining thereafter.

      MS is considered an autoimmune disease, whereby the body’s own immune system (which normally targets and destroys substances foreign the body) mistakenly attacks normal tissues.  In MS, the immune system targets the brain and spinal cord, the two components of the central nervous system.   The most common symptoms of MS include:
  • Fatigue (most common), mental fatigue, drowsiness,
  • Tingling, numbness, tremors;
  • Sudden onset of paralysis;
  • Loss of balance, coordination, dizziness & light headed;
  • Weakness in one or more limbs;
  • Blurred or double vision; optic neuritis;
  • Slurred speech; swallowing problems;
  • Slowed thinking, decreased concentration and memory.


Methodology & Test Subjects
Three volunteers were chosen.  Each was diagnosed by a physician, suffered from Multiple Sclerosis for a multitude of years and was in a very degenerative condition.  The volunteers were given polysaccharides/polypeptides to take three times daily for a period of 30-60 days.
            Patient #1 & #2 had blood urine Oxidative Stress Profiles completed at days 0, 30, & 60.  They filled out symptom questionnaires at days 0, 30, & 60.  They filled out symptom questionnaires at days 0 & 30.  It was not necessary to complete a 60 day post test symptom questionnaire as they had few symptoms remaining at that point.
            Patient #3 had a day 0 & 60 blood and urine Oxidative Stress Profile completed and also filled out the symptom questionnaires at days 0 & 60.  All results are included in this clinical report.  The following are the protocols that were adhered to.

Protocol
Test subjects met the following criteria:
  • No age limitation
  • Experiencing all of the following:
    The conditions or imbalances on the MS questionnaires.  (Each patient had been diagnosed with chronic degenerative Multiple Sclerosis).
    Duration of study; 0,30, & 6- days pre and post testing
    Pre and post testing was performed as follows:
  • Interview for qualification;
  • Physical and symptom evaluation;
  • Completed a MS questionnaire, before and after;
  • Pre and post Oxidative Stress Panel (blood and urine).
Intake (Diet, medication and supplementation).
  • Maintained:  current eating habits, medications, vitamins, other supplements
  • Variable compliance on food elimination: dairy products, sugar, caffeine, alcohol and tobacco for duration of the study (optional)
Lifestyle
  • Maintained current lifestyle
  • Avoided long distance air travel
Patients completed Informed Consent Form
Dosage:  5 grams (1 tsp.), 3 times a day
The physical, symptom and laboratory measures were all completed
2.0   Inclusion/Exclusion  criteria was followed


Laboratory Results
In one patient, who also had diabetes (type 2), self testing indicated that there was a significant decrease in blood sugar from over 200, down to the low 100’s on a consistent basis.  This could be due in part to current research demonstrating that the addition of SOD (superoxide dismutase) and catalase to cultures of pancreatic islets exposed simultaneously to alloxan resulted in a partial restoration of insulin synthesis.
            Polysaccharides/polypeptides delay the production of Single Molecule Sugar (Glucose).  This delay will slow down the increase of the sugar in the blood, while the amino acids will help the pancreas secrete adequate insulin so sugars are brought to the cells at a more efficient rate, thereby, bringing normalcy in the blood sugar level.
            The patients did not perform any internal body cleansing or detoxification procedures to enhance the elimination of toxins, which would have been the recommended protocol.


  
Conclusion

All three individuals participating in the study experienced significant reductions in their Multiple Schlerosis related symptoms.  A reduction in degenerative disease causing free radicals and an increase in antioxidants such as SOD (superoxide dismutase) and the glutathione were demonstrated in the Oxidative Stress Profiles.  As the SOD antioxidant increases were almost triple in the first thirty days and then declined afterward, it would most likely be attributed to the metabolism of the free radicals, a metabolic balancing, or any of the reasons previously suggested in this study.
            One of the patients (with diabetes) experienced immediate and continued improvements in blood sugar regulation.
            Patients experienced a normalization of the wright (decrease in obesity in one, and maintaining of weight in others who did not wish to lose weight).
            The results of this study along with the in-vitro research would demonstrate cellular protection from particular neurotoxins known to have a deleterious and degenerative effect on all nerve cells, (i.e. beta amyloids, glutamates, and peroxides).  The nutrients in polysaccharides/polypeptides would also provide the cellular fuel necessary for cellular communication and regeneration.

References
  • Laboratory report from Pacific Lab Services, Report NO: (396-3971?LS 2001 Date: February 19th, 2001.
  • Mesco, ER, Timiras, PS, “Tau-ubiquitin protein conjugates 1 a human cell line,” Mech Ageig Dev, 1919; 61(1): 1-9.
  • Beal, MF, (1995), “Aging, energy, and oxidative stress in neurodegenative disease,” Ann, Neuro, 38, 357-366
  • Mattson, MP, (1994), “Mechanism of neuronal degeneration and preventative approaches,” Neurobiol Aging, 15(suppl.2) S121-S125.